Reaction: xylitol + NADP+ = L-xylulose + NADPH + H+
For diagram of reaction click here.
Other name(s): xylitol dehydrogenase (ambiguous)
Systematic name: xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming)
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9028-17-5
References:
1. Doten, R.C. and Mortlock, R.P. Characterization of xylitol-utilizing mutants of Erwinia uredovora. J. Bacteriol. 161 (1985) 529-533. [PMID: 2981816]
2. Hickman, J. and Ashwell, G. A sensitive and stereospecific enzymatic assay for xylulose. J. Biol. Chem. 234 (1959) 758-761.
3. Hollmann, S. and Touster, O. The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria. J. Biol. Chem. 225 (1957) 87-102.
4. Touster, O., Reynolds, V.H. and Hutcheson, R.M. The reduction of L-xylulose to xylitol by guinea pig liver mitochondria. J. Biol. Chem. 221 (1956) 697-709.