IUBMB Enzyme Nomenclature


Accepted name: pyridoxal 4-dehydrogenase

Reaction: pyridoxal + NAD+ = 4-pyridoxolactone + NADH + H+

For diagram of reaction click here.

Other name(s): pyridoxal dehydrogenase

Systematic name: pyridoxal:NAD+ 4-oxidoreductase

Comments: The enzyme acts on the hemiacetal form of the substrate.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-39-8


1. Burg, R.W. and Snell, E.E. The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase. J. Biol. Chem. 244 (1969) 2585-2589. [PMID: 4306030]

[EC created 1972]

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