IUBMB Enzyme Nomenclature


Accepted name: GDP-mannose 6-dehydrogenase

Reaction: GDP-D-mannose + 2 NAD+ + H2O = GDP-D-mannuronate + 2 NADH + 2 H+

Other name(s): guanosine diphosphomannose dehydrogenase; GDP mannose dehydrogenase; guanosine diphosphomannose dehydrogenase; guanosine diphospho-D-mannose dehydrogenase

Systematic name: GDP-D-mannose:NAD+ 6-oxidoreductase

Comments: Also acts on the corresponding deoxynucleoside diphosphate derivative as a substrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-63-8


1. Preiss, J. Sugar nucleotide reaction in Arthrobacter. II. Biosynthesis of guanosine diphosphomannuronate. J. Biol. Chem. 239 (1964) 3127-3132.

[EC created 1972]

Return to EC 1.1.1 home page
Return to EC 1.1 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page