IUBMB Enzyme Nomenclature


Accepted name: dihydrobunolol dehydrogenase

Reaction: (±)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ = (±)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+

Other name(s): bunolol reductase

Systematic name: (±)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase

Comments: Also acts, more slowly, with NAD+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 62213-61-0


1. Leinweber, F.-J., Greenough, R.C., Schwender, C.F., Kaplan, H.R. and DiCarlo, F.J. Bunolol metabolism by cell-free preparations of human liver: biosynthesis of dihydrobunolol. Xenobiotica 2 (1972) 191-202. [PMID: 4560367]

[EC created 1976]

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