IUBMB Enzyme Nomenclature


Accepted name: glucuronolactone reductase

Reaction: L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH + H+

Other name(s): GRase; gulonolactone dehydrogenase

Systematic name: L-gulono-1,4-lactone:NADP+ 1-oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9028-30-2


1. Suzuki, K., Mano, Y. and Shimazono, N. Conversion of L-gulonolactone to L-ascorbic acid; properties of the microsomal enzyme in rat liver. J. Biochem. (Tokyo) 48 (1960) 313-315.

[EC created 1961]

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