IUBMB Enzyme Nomenclature


Accepted name: mannose-6-phosphate 6-reductase

Reaction: D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + NADPH + H+

Other name(s): NADPH-dependent mannose 6-phosphate reductase; mannose-6-phosphate reductase; 6-phosphomannose reductase; NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase; NADPH-dependent M6P reductase; NADPH-mannose-6-P reductase

Systematic name: D-mannitol-1-phosphate:NADP+ 6-oxidoreductase

Comments: Involved in the biosynthesis of mannitol in celery (Apium graveolens) leaves.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 88747-79-9


1. Rumpho, M.E., Edwards, G.E. and Loescher, W.H. A pathway for photosynthetic carbon flow to mannitol in celery leaves – Activity and localization of key enzymes. Plant Physiol. 73 (1983) 869-873.

[EC created 1989]

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