IUBMB Enzyme Nomenclature


Accepted name: 4-hydroxycyclohexanecarboxylate dehydrogenase

Reaction: trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + NADH + H+

Other name(s): trans-4-hydroxycyclohexanecarboxylate dehydrogenase

Systematic name: trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase

Comments: The enzyme from Corynebacterium cyclohexanicum is highly specific for the trans-4-hydroxy derivative.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 67272-36-0


1. Obata, H., Uebayashi, M. and Kaneda, T. Purification and properties of 4-hydroxycyclohexanecarboxylate dehydrogenase from Corynebacterium cyclohexanicum. Eur. J. Biochem. 174 (1988) 451-458. [PMID: 3292236]

[EC created 1990]

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