IUBMB Enzyme Nomenclature


Accepted name: N-acetylhexosamine 1-dehydrogenase

Reaction: N-acetyl-α-D-glucosamine + NAD+ = N-acetyl-D-glucosaminate + NADH + H+

Other name(s): N-acetylhexosamine dehydrogenase; N-acetyl-D-hexosamine dehydrogenase

Systematic name: N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase

Comments: Also acts on N-acetylgalactosamine and, more slowly, on N-acetylmannosamine. Anomeric specificity was tested with N-acetyl-D-glucosamine, and it was shown that the enzyme is specific for the α anomer.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 122785-18-6


1. Horiuchi, T. and Kurokawa, T. Purification and characterization of N-acetyl-D-hexosamine dehydrogenase from Pseudomonas sp no 53. Agric. Biol. Chem. 53 (1989) 1919-1925.

[EC created 1992]

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