IUBMB Enzyme Nomenclature


Accepted name: glyoxylate reductase

Reaction: glycolate + NAD+ = glyoxylate + NADH + H+

For diagram of reaction click here.

Other name(s): NADH-glyoxylate reductase; glyoxylic acid reductase; NADH-dependent glyoxylate reductase

Systematic name: glycolate:NAD+ oxidoreductase

Comments: Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, vMetacyc, PDB, CAS registry number: 9028-32-4


1. Zelitch, I. Oxidation and reduction of glycolic and glyoxylic acids in plants. II. Glyoxylic acid reductase. J. Biol. Chem. 201 (1953) 719-726.

2. Zelitch, I. The isolation and action of crystalline glyoxylic acid reductase from tobacco leaves. J. Biol. Chem. 216 (1955) 553-575.

[EC created 1961]

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