IUBMB Enzyme Nomenclature


Accepted name: 1,5-anhydro-D-fructose reductase

Reaction: 1,5-anhydro-D-glucitol + NADP+ = 1,5-anhydro-D-fructose + NADPH + H+

Systematic name: 1,5-anhydro-D-glucitol:NADP+ oxidoreductase

Comments: Also reduces pyridine-3-aldehyde and 2,3-butanedione. Acetaldehyde, 2-dehydroglucose (glucosone) and glucuronate are poor substrates, but there is no detectable action on glucose, mannose and fructose.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 206138-19-4


1. Sakuma, M., Kametani, S. and Akanuma, H. Purification and some properties of a hepatic NADPH-dependent reductase that specifically acts on 1,5-anhydro-D-fructose. J. Biochem. (Tokyo) 123 (1998) 189-193.

[EC created 2000]

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