IUBMB Enzyme Nomenclature


Accepted name: 3-methylbutanal reductase

Reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+

Systematic name: 3-methylbutanol:NAD(P)+ oxidoreductase

Comments: The enzyme purified from Saccharomyces cerevisiae catalyses the reduction of a number of straight-chain and branched aldehydes, as well as some aromatic aldehydes.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 214265-44-8


1. van Iersel, M.F.M., Eppink, M.H.M., van Berkel, W.J.H., Rombouts, F.M. and Abee, T. Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae. Appl. Environ. Microbiol. 63 (1997) 4079-4082. [PMID: 9327572]

2. Ven Nedervelde, L., Verlinden, V., Philipp, D. and Debourg, A. Purification and characterization of yeast 3-methyl butanal reductases involved in the removal of wort carbonyls during fermentation. Proc. 26th Congr.-Eur. Brew. Conv. (1997) 447-454.

[EC created 2000]

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