IUBMB Enzyme Nomenclature


Accepted name: sulfopropanediol 3-dehydrogenase

Reaction: (R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O = (R)-3-sulfolactate + 2 NADH + 2 H+

Other name(s): DHPS 3-dehydrogenase (sulfolactate forming); 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming); dihydroxypropanesulfonate 3-dehydrogenase; hpsN (gene name)

Systematic name: (R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase

Comments: The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Mayer, J., Huhn, T., Habeck, M., Denger, K., Hollemeyer, K. and Cook, A.M. 2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase. Microbiology 156 (2010) 1556-1564. [PMID: 20150239]

[EC created 2011]

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