IUBMB Enzyme Nomenclature


Accepted name: 3-hydroxyisobutyrate dehydrogenase

Reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+

Other name(s): β-hydroxyisobutyrate dehydrogenase

Systematic name: 3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9028-39-1


1. Robinson, W.G. and Coon, M.J. Purification and properties of β-hydroxyisobutyric dehydrogenase. J. Biol. Chem. 225 (1957) 511-521.

[EC created 1961]

Return to EC 1.1.1 home page
Return to EC 1.1 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page