IUBMB Enzyme Nomenclature


Accepted name: UDP-N-acetyl-D-mannosamine dehydrogenase

Reaction: UDP-N-acetyl-α-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-α-D-mannosaminuronate + 2 NADH + 2 H+

For diagram of reaction click here.

Other name(s): UDP-ManNAc 6-dehydrogenase; wecC (gene name)

Systematic name: UDP-N-acetyl-α-D-mannosamine:NAD+ 6-oxidoreductase

Comments: Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Namboori, S.C. and Graham, D.E. Acetamido sugar biosynthesis in the Euryarchaea. J. Bacteriol. 190 (2008) 2987-2996. [PMID: 18263721]

[EC created 2012]

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