IUBMB Enzyme Nomenclature

EC 1.1.1.354

Accepted name: farnesol dehydrogenase (NAD+)

Reaction: (2E,6E)-farnesol + NAD+ = (2E,6E)-farnesal + NADH + H+

For diagram of reaction click here.

Other name(s): NAD+-farnesol dehydrogenase

Systematic name: (2E,6E)-farnesol:NAD+ 1-oxidoreductase

Comments: The enzyme from the prune mite Carpoglyphus lactis also acts on geraniol with greater activity [cf. EC 1.1.1.347, geraniol dehydrogenase (NAD+)]. Unlike EC 1.1.1.216, farnesol dehydrogenase (NADP+), this enzyme cannot use NADP+ as cofactor.

Links to other databases: BRENDA, EXPASY, KEGG Metacyc, CAS registry number:

References:

1. Noge, K., Kato, M., Mori, N., Kataoka, M., Tanaka, C., Yamasue, Y., Nishida, R. and Kuwahara, Y. Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae). FEBS J. 275 (2008) 2807-2817. [PMID: 18422649]

[EC 1.1.1.354 created 2013]


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