IUBMB Enzyme Nomenclature


Accepted name: acetoacetyl-CoA reductase

Reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+

For diagram of reaction click here or click here.

Other name(s): acetoacetyl coenzyme A reductase; hydroxyacyl coenzyme-A dehydrogenase; NADP-linked acetoacetyl CoA reductase; NADPH:acetoacetyl-CoA reductase; D(–)-β-hydroxybutyryl CoA-NADP oxidoreductase; short chain β-ketoacetyl(acetoacetyl)-CoA reductase; β-ketoacyl-CoA reductase; D-3-hydroxyacyl-CoA reductase; (R)-3-hydroxyacyl-CoA dehydrogenase

Systematic name: (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9028-41-5


1. Wakil, S.J. and Bressler, R. Studies on the mechanism of fatty acid synthesis. X. Reduced triphosphopyridine nucleotide-acetoacetyl coenzyme A reductase. J. Biol. Chem. 237 (1962) 687-693.

[EC created 1961]

Return to EC 1.1.1 home page
Return to EC 1.1 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page