IUBMB Enzyme Nomenclature


Accepted name: L-idonate 5-dehydrogenase (NAD+)

Reaction: L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+

Systematic name: L-idonate:NAD+ oxidoreductase

Comments: Involved in the catabolism of ascorbate (vitamin C) to tartrate. No activity is observed with NADP+ (cf. EC, L-idonate 5-dehydrogenase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. DeBolt, S., Cook, D.R. and Ford, C.M. L-Tartaric acid synthesis from vitamin C in higher plants. Proc. Natl. Acad. Sci. USA 103 (2006) 5608-5613. [PMID: 16567629]

[EC created 2013]

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