Reaction: L-rhamnose + NADP+ = L-rhamnono-1,4-lactone + NADPH + H+
Systematic name: L-rhamnose:NADP+ 1-oxidoreductase
Comments: The enzyme from the archaeon Thermoplasma acidophilum is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 18.104.22.168, L-rhamnose 1-dehydrogenase, which is specific for NAD+.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Kim, S.M., Paek, K.H. and Lee, S.B. Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum. Extremophiles 16 (2012) 447-454. [PMID: 22481639]