IUBMB Enzyme Nomenclature


Accepted name: L-rhamnose 1-dehydrogenase (NADP+)

Reaction: L-rhamnose + NADP+ = L-rhamnono-1,4-lactone + NADPH + H+

Systematic name: L-rhamnose:NADP+ 1-oxidoreductase

Comments: The enzyme from the archaeon Thermoplasma acidophilum is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC, L-rhamnose 1-dehydrogenase, which is specific for NAD+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Kim, S.M., Paek, K.H. and Lee, S.B. Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum. Extremophiles 16 (2012) 447-454. [PMID: 22481639]

[EC created 2014]

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