IUBMB Enzyme Nomenclature


Accepted name: D-threitol dehydrogenase (NAD+)

Reaction: D-threitol + NAD+ = D-erythrulose + NADH + H+

Other name(s): dthD (gene name)

Systematic name: D-threitol:NAD+ oxidoreductase

Comments: The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of D-threitol.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Huang, H., Carter, M.S., Vetting, M.W., Al-Obaidi, N., Patskovsky, Y., Almo, S.C. and Gerlt, J.A. A general strategy for the discovery of metabolic pathways: D-threitol, L-threitol, and erythritol utilization in Mycobacterium smegmatis. J. Am. Chem. Soc. 137 (2015) 14570-14573. [PMID: 26560079]

[EC created 2016]

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