IUBMB Enzyme Nomenclature


Accepted name: 2-alkyl-3-oxoalkanoate reductase

Reaction: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+ = an (R)-2-alkyl-3-oxoalkanoate + NADPH + H+

Other name(s): oleD (gene name)

Systematic name: (2R,3S)-2-alkyl-3-hydroxyalkanoate:NADP+ oxidoreductase

Comments: The enzyme, found in certain bacterial species, is part of a pathway for the production of olefins.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Bonnett, S.A., Papireddy, K., Higgins, S., del Cardayre, S. and Reynolds, K.A. Functional characterization of an NADPH dependent 2-alkyl-3-ketoalkanoic acid reductase involved in olefin biosynthesis in Stenotrophomonas maltophilia. Biochemistry 50 (2011) 9633-9640. [PMID: 21958090]

[EC created 2017]

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