IUBMB Enzyme Nomenclature


Accepted name: 6-dehydroglucose reductase

Reaction: D-glucose + NADP+ = 6-dehydro-D-glucose + NADPH + H+

Glossary: quinovose = 6-deoxy-D-glucopyranose

Other name(s): D-glucose 6-dehydrogenase; smoB (gene name); squF (gene name)

Systematic name: D-glucose:NADP+ 6-oxidoreductase

Comments: The enzyme, characterized from alphaproteobacteria, is involved in a D-sulfoquinovose degradation pathway.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Sharma, M., Lingford, J.P., Petricevic, M., Snow, A.J.D., Zhang, Y., Jarva, M.A., Mui, J.W., Scott, N.E., Saunders, E.C., Mao, R., Epa, R., da Silva, B.M., Pires, D.E.V., Ascher, D.B., McConville, M.J., Davies, G.J., Williams, S.J. and Goddard-Borger, E.D. Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria. Proc. Natl. Acad. Sci. USA 119 (2022) e2116022119. [PMID: 35074914]

2. Liu, J., Wei, Y., Ma, K., An, J., Liu, X., Liu, Y., Ang, E.L., Zhao, H. and Zhang, Y. Mechanistically diverse pathways for sulfoquinovose degradation in bacteria. ACS Catal. 11 (2021) 14740-14750.

[EC created 2022]

Return to EC 1.1.1 home page
Return to EC 1.1 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page