Reaction: questin hydroquinone + NADP+ = questin + NADPH + H+
Glossary: questin = 1,6-dihydroxy-8-methoxy-3-methylanthracene-9,10-dione
Other name(s): gedF (gene name)
Systematic name: questin hydroquinone:NADP+ 10-oxidoreductase
Comments: The enzyme, characterized from the fungus Aspergillus terreus, catalyses a step in the biosynthesis of (+)-geodin.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Qi, F., Zhang, W., Xue, Y., Geng, C., Huang, X., Sun, J. and Lu, X. Bienzyme-catalytic and dioxygenation-mediated anthraquinone ring opening. J. Am. Chem. Soc. 143 (2021) 16326-16331. [PMID: 34586791]