IUBMB Enzyme Nomenclature

EC 1.1.1.444

Accepted name: sulfofucose 1-dehydrogenase

Reaction: sulfofucose + NAD+ = 6-deoxy-6-sulfo-D-galactono-1,5-lactone + NADH + H+

Glossary: sulfofucose = 6-deoxy-6-sulfo-D-galactopyranose

Other name(s): sulfofucose dehydrogenase; SfcH

Systematic name: 6-deoxy-6-sulfo-D-galactopyranose:NAD+ 1-oxidoreductase

Comments: This enzyme, characterized from the bacterium Paracoccus wurundjeri strain Merri, participates in a sulfofucose degradation pathway. Activity with NADP+ is 28% of that with NAD+. cf. EC 1.1.1.390, sulfoquinovose 1-dehydrogenase.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Stewart, A.WE., Li, J., Lee, M., Lewis, J.M., Herisse, M., Hofferek, V., McConville, M.J., Pidot, S.J., Scott, N.E. and Williams, S.J. Tandem sulfofucolytic-sulfolactate sulfolyase pathway for catabolism of the rare sulfosugar sulfofucose. mBio 16 (2025) e0184025. [PMID: 40823846]

[EC 1.1.1.444 created 2025]


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