IUBMB Enzyme Nomenclature


Accepted name: D-galactose 1-dehydrogenase

Reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+

Other name(s): D-galactose dehydrogenase; β-galactose dehydrogenase (ambiguous); NAD+-dependent D-galactose dehydrogenase

Systematic name: D-galactose:NAD+ 1-oxidoreductase

Comments: This enzyme is part of the De Ley-Doudoroff pathway, which is used by some bacteria during growth on D-galactose.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9028-54-0


1. De Ley, J. and Doudoroff, M. The metabolism of D-galactose in Pseudomonas saccharophila. J. Biol. Chem. 227 (1957) 745-757. [PMID: 13462997]

2. Hu, A.S.L. and Cline, A.L. The regulation of some sugar dehydrogenases in a pseudomonad. Biochim. Biophys. Acta 93 (1964) 237-245. [PMID: 14251301]

[EC created 1961, modified 2011]

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