IUBMB Enzyme Nomenclature


Accepted name: D-xylulose reductase

Reaction: xylitol + NAD+ = D-xylulose + NADH + H+

Other name(s): NAD-dependent xylitol dehydrogenase; xylitol dehydrogenase (ambiguous); erythritol dehydrogenase; 2,3-cis-polyol(DPN) dehydrogenase (C3-5); pentitol-DPN dehydrogenase (ambiguous); xylitol-2-dehydrogenase;

Systematic name: xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)

Comments: Also acts as an L-erythrulose reductase.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9028-16-4


1. Chiang, C. and Knight, S.G. A new pathway of pentose metabolism. Biochem. Biophys. Res. Commun. 3 (1960) 554-559.

2. Hickman, J. and Ashwell, G. A sensitive and stereospecific enzymatic assay for xylulose. J. Biol. Chem. 234 (1959) 758-761.

3. Jakoby, W.B. and Fredericks, J. Erythritol dehydrogenase from Aerobacter aerogenes. Biochim. Biophys. Acta 48 (1961) 26-32.

[EC created 1961]

Return to EC 1.1.1 home page
Return to EC 1.1 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page