IUBMB Enzyme Nomenclature


Accepted name: pyranose oxidase

Reaction: D-glucose + O2 = 2-dehydro-D-glucose + H2O2

Other name(s): glucose 2-oxidase; pyranose-2-oxidase

Systematic name: pyranose:oxygen 2-oxidoreductase

Comments: A flavoprotein (FAD). Also oxidizes D-xylose, L-sorbose and D-glucono-1,5-lactone, which have the same ring conformation and configuration at C-2, C-3 and C-4.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-80-9


1. Janssen, F.W. and Ruelius, H.W. Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. II. Specificity and characterization of reaction products. Biochim. Biophys. Acta 167 (1968) 501-510. [PMID: 5722278]

2. Machida, Y. and Nakanishi, T. Purification and properties of pyranose oxidase from Coriolus versicolor. Agric. Biol. Chem. 48 (1984) 2463-2470.

3. Neidleman, S.L., Amon, W.F., Jr. and Geigert, J. Process for the production of fructose. Patent US4246347, 1981. Chem. Abstr. 94 (1981) 207379 (PDF).

4. Ruelius, H.W., Kerwin, R.M. and Janssen, F.W. Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. I. Isolation and purification. Biochim. Biophys. Acta 167 (1968) 493-500. [PMID: 5725162]

[EC created 1972]

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