IUBMB Enzyme Nomenclature


Accepted name: 4-hydroxymandelate oxidase (decarboxylating)

Reaction: (S)-4-hydroxymandelate + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2

Glossary: (S)-4-hydroxymandelate = (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate

Other name(s): L-4-hydroxymandelate oxidase (decarboxylating); (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase; (S)-4-hydroxymandelate:oxygen 1-oxidoreductase; 4-hydroxymandelate oxidase

Systematic name: (S)-4-hydroxymandelate:oxygen 1-oxidoreductase (decarboxylating)

Comments: A flavoprotein (FAD), requires Mn2+. The enzyme from the bacterium Pseudomonas putida-is involved in the degradation of mandelate.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 60976-30-9


1. Bhat, S.G. and Vaidyanathan, C.S. Purification and properties of L-4-hydroxymandelate oxidase from Pseudomonas convexa. Eur. J. Biochem. 68 (1976) 323-331. [PMID: 976259]

[EC created 1984, modified 2014]

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