IUBMB Enzyme Nomenclature


Accepted name: L-2-hydroxyglutarate dehydrogenase

Reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor

Other name(s): α-ketoglutarate reductase; α-hydroxyglutarate dehydrogenase; L-α-hydroxyglutarate dehydrogenase; hydroxyglutaric dehydrogenase; α-hydroxyglutarate oxidoreductase; L-α-hydroxyglutarate:NAD+ 2-oxidoreductase; α-hydroxyglutarate dehydrogenase (NAD+ specific); (S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase

Systematic name: (S)-2-hydroxyglutarate:acceptor 2-oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9028-80-2


1. Weil-Malherbe, H. The oxidation of l(-)α-hydroxyglutaric acid in animal tissues. Biochem. J. 31 (1937) 2080-2094. [PMID: 16746551]

[EC created 1961, modified 2013]

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