IUBMB Enzyme Nomenclature


Accepted name: dehydrogluconate dehydrogenase

Reaction: 2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced acceptor

Other name(s): ketogluconate dehydrogenase; α-ketogluconate dehydrogenase; 2-keto-D-gluconate dehydrogenase; 2-oxogluconate dehydrogenase

Systematic name: 2-dehydro-D-gluconate:acceptor 2-oxidoreductase

Comments: A flavoprotein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9028-82-4


1. Datta, A.G. and Katznelson, H. The oxidation of 2-ketogluconate by a partially purified enzyme from Acetobacter melanogenum. Arch. Biochem. Biophys. 65 (1956) 576-578.

2. Shinagawa, E. and Ameyama, M. 2-Keto-D-gluconate dehydrogenase from Gluconobacter melanogenus, membrane-bound. Methods Enzymol. 89 (1982) 194-198.

[EC created 1961, modified 1989]

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