IUBMB Enzyme Nomenclature

EC 1.13.11.40

Accepted name: arachidonate 8-lipoxygenase

Reaction: arachidonate + O2 = (5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-tetraenoate

Other name(s): 8-lipoxygenase; 8(R)-lipoxygenase

Systematic name: arachidonate:oxygen 8-oxidoreductase

Comments: From the coral Pseudoplexaura porosa.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 100900-72-9

References:

1. Bundy, G.L., Nidy, E.G., Epps, D.E., Mizsak, S.A. and Wnuk, R.J. Discovery of an arachidonic acid C-8 lipoxygenase in the gorgonian coral Pseudoplexaura porosa. J. Biol. Chem. 261 (1986) 747-751. [PMID: 2867091]

[EC 1.13.11.40 created 1989]


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