IUBMB Enzyme Nomenclature


Accepted name: 1,2-dihydroxynaphthalene dioxygenase

Reaction: naphthalene-1,2-diol + O2 = 2-hydroxy-2H-chromene-2-carboxylate

For diagram of reaction, click here

Other name(s): 1,2-DHN dioxygenase; DHNDO; 1,2-dihydroxynaphthalene oxygenase; 1,2-dihydroxynaphthalene:oxygen oxidoreductase

Systematic name: naphthalene-1,2-diol:oxygen oxidoreductase

Comments: This enzyme is involved in naphthalene degradation. Requires Fe2+.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Kuhm, A.E., Stolz, A., Ngai, K.L. and Knackmuss, H.J. Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids. J. Bacteriol. 173 (1991) 3795-3802. [PMID: 2050635]

2. Keck, A., Conradt, D., Mahler, A., Stolz, A., Mattes, R. and Klein, J. Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6. Microbiology 152 (2006) 1929-1940. [PMID: 16804169]

3. Patel, T.R. and Barnsley, E.A. Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase. J. Bacteriol. 143 (1980) 668-673. [PMID: 7204331]

[EC created 2010]

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