IUBMB Enzyme Nomenclature


Accepted name: 8'-apo-β-carotenoid 14',13'-cleaving dioxygenase

Reaction: 8'-apo-β-carotenol + O2 = 14'-apo-β-carotenal + an uncharacterized product

For diagram of reaction click here.

Other names: 8'-apo-β-carotenol:O2 oxidoreductase (14',13'-cleaving)

Systematic name(s): 8'-apo-β-carotenol:oxygen oxidoreductase (14',13'-cleaving)

Comments: A thiol-dependent enzyme isolated from rat and rabbit. Unlike EC, β-carotene-15,15'-monooxygenase, it is not active towards β-carotene. The secondary product has not been characterized, but may be (3E,5E)-7-hydroxy-6-methylhepta-3,5-dien-2-one.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 198028-39-6


1. Dmitrovskii, A.A., Gessler, N.N., Gomboeva, S.B., Ershov, Yu.V. and Bykhovsky, V.Ya. Enzymatic oxidation of β-apo-8'-carotenol to β-apo-14'-carotenal by an enzyme different from β-carotene-15,15'-dioxygenase. Biochemistry (Mosc) 62 (1997) 787-792. [PMID: 9331970]

[EC created 2000 as EC, transferred 2012 to EC]

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