IUBMB Enzyme Nomenclature


Accepted name: 9-cis-β-carotene 9',10'-cleaving dioxygenase

Reaction: 9-cis-β-carotene + O2 = 9-cis-10'-apo-β-carotenal + β-ionone

For diagram of reaction click here.

Glossary: β-ionone = (3E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one

Other name(s): CCD7 (gene name); MAX3 (gene name); NCED7 (gene name); 9-cis-β-carotene:O2 oxidoreductase (9',10'-cleaving)

Systematic name: 9-cis-β-carotene:oxygen oxidoreductase (9',10'-cleaving)

Comments: Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Booker, J., Auldridge, M., Wills, S., McCarty, D., Klee, H. and Leyser, O. MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule. Curr. Biol. 14 (2004) 1232-1238. [PMID: 15268852]

2. Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H., Beyer, P. and Al-Babili, S. The path from β-carotene to carlactone, a strigolactone-like plant hormone. Science 335 (2012) 1348-1351. [PMID: 22422982]

[EC created 2012]

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