Reaction: all-trans-10'-apo-β-carotenal + O2 = 13-apo-β-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial
For diagram of reaction click here.
Other name(s): CCD8 (gene name); MAX4 (gene name); NCED8 (gene name); all-trans-10'-apo-β-carotenal:O2 oxidoreductase (13,14-cleaving)
Systematic name: all-trans-10'-apo-β-carotenal:oxygen oxidoreductase (13,14-cleaving)
Comments: Requires Fe2+. The enzyme from the plant Arabidopsis thaliana also catalyses EC 1.13.11.69, carlactone synthase, 10-fold faster.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Schwartz, S.H., Qin, X. and Loewen, M.C. The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching. J. Biol. Chem. 279 (2004) 46940-46945. [PMID: 15342640]