IUBMB Enzyme Nomenclature


Accepted name: 8'-apo-carotenoid 13,14-cleaving dioxygenase

Reaction: 8'-apo-β-carotenal + O2 = 13-apo-β-carotenone + 2,6-dimethyldeca-2,4,6,8-tetraenedial

For diagram of reaction click here.

Other name(s): NACOX1 (gene name)

Systematic name: 8'-apo-β-carotenal:oxygen 13,14-dioxygenase (bond-cleaving)

Comments: Isolated from the bacterium Novosphingobium aromaticivorans. It is less active with 4'-apo-β-carotenal and γ-carotene.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Kim, Y.S., Seo, E.S. and Oh, D.K. Characterization of an apo-carotenoid 13,14-dioxygenase from Novosphingobium aromaticivorans that converts β-apo-8'-carotenal to β-apo-13-carotenone. Biotechnol. Lett. 34 (2012) 1851-1856. [PMID: 22711425]

[EC created 2015]

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