IUBMB Enzyme Nomenclature


Accepted name: 2-oxoadipate dioxygenase/decarboxylase

Reaction: 2-oxoadipate + O2 = (R)-2-hydroxyglutarate + CO2

Other name(s): ydcJ (gene name)

Systematic name: 2-oxoadipate dioxygenase/carboxy lyase

Comments: The enzyme, characterized from the bacterium Pseudomonas putida, is involved in an L-lysine catabolic pathway. Contains Fe(II).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Thompson, M.G., Blake-Hedges, J.M., Cruz-Morales, P., Barajas, J.F., Curran, S.C., Eiben, C.B., Harris, N.C., Benites, V.T., Gin, J.W., Sharpless, W.A., Twigg, F.F., Skyrud, W., Krishna, R.N., Pereira, J.H., Baidoo, E.EK., Petzold, C.J., Adams, P.D., Arkin, A.P., Deutschbauer, A.M. and Keasling, J.D. Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism. mBio 10 (2019) . [PMID: 31064836]

[EC created 2022]

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