IUBMB Enzyme Nomenclature


Accepted name: Cypridina-luciferin 2-monooxygenase

Reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 +

Glossary: Cypridina-luciferin = (3-{3,7-dihydro-6-(1H-indol-3-yl)-2-[(S)-1-methylpropyl]-3-oxoimidazo[1,2-a]pyrazin-8-yl}propyl)guanidine

For diagram click here.

Other name(s): Cypridina-type luciferase; luciferase (Cypridina luciferin); Cypridina luciferase

Systematic name: Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)

Comments: Cypridina is a bioluminescent crustacea. The luciferins (and presumably the luciferases, since they cross-react) of some luminous fish (e.g. Apogon, Parapriacanthus, Porichthys) are apparently similar. The enzyme may be assayed by measurement of light emission.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 61969-99-1


1. Cormier, M.J., Crane, J.M.,Jr. and Nakano, Y Evidence for the identity of the luminescent systems of Porichthys porosissimus (fish) and Cypridina hilgendorfii (crustacean). Biochem. Biophys. Res. Commun. 29 (1967) 747-752. [PMID: 5624784]

2. Karpetsky, T.P. and White, E.H. The synthesis of Cypridina etioluciferamine and the proof of the structure of Cypridina luciferin. Tetrahedron 29 (1973) 3761-3773.

3. Kishi, Y., Goto, T., Hirata, Y., Shiromura, O. and Johnson, F.H. Cypridina bioluminescence. I. Structure of Cypridina luciferin. Tetrahedron Lett. (1966) 3427-3436.

4. Tsuji, F.I., Lynch, R.V. and Stevens, C.L. Some properties of luciferase from the bioluminescent crustacean, Cypridina hilgendorfii. Biochemistry 13 (1974) 5204-5209. [PMID: 4433517]

[EC created 1976, modified 1982]

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