IUBMB Enzyme Nomenclature

EC 1.13.12.9

Accepted name: phenylalanine 2-monooxygenase

Reaction: L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O

Other name(s): L-phenylalanine oxidase (deaminating and decarboxylating); phenylalanine (deaminating, decarboxylating)oxidase

Systematic name: L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)

Comments: The reaction shown above is about 80% of the reaction catalysed; the remaining 20% is:

    L-phenylalanine + O2 + H2O = 3-phenylpyruvic acid + ammonia + H2O2

a reaction similar to that of EC 1.4.3.2, L-amino-acid oxidase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 190396-37-3

References:

1. Koyama, H. Purification and characterization of a novel L-phenylalanine oxidase (deaminating and decarboxylating) from Pseudomonas sp. P-501. J. Biochem. (Tokyo) 92 (1982) 1235-1240. [PMID: 7174643]

2. Koyama, H. Oxidation and oxygenation of L-amino acids catalyzed by a L-phenylalanine oxidase (deaminating and decarboxylating) from Pseudomonas sp. P-501. J. Biochem. (Tokyo) 96 (1984) 421-427. [PMID: 6501250]

3. Koyama, H. A simple and rapid enzymatic determination of L-phenylalanine with a novel L-phenylalanine oxidase (deaminating and decarboxylating) from Pseudomonas sp. P-501. Clin. Chim. Acta 1361 (1984) 131-136. [PMID: 6692570]

4. Koyama, H. and Suzuki, H. Spectral and kinetic studies on Pseudomonas L-phenylalanine oxidase (deaminating and decarboxylating). J. Biochem. (Tokyo) 100 (1986) 859-866. [PMID: 3818566]

[EC 1.13.12.9 created 1986, modified 2003]


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