IUBMB Enzyme Nomenclature


Accepted name: taurine dioxygenase

Reaction: taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2

Other name(s) 2-aminoethanesulfonate dioxygenase; α-ketoglutarate-dependent taurine dioxygenase

Systematic name: taurine, 2-oxoglutarate::oxygen oxidoreductase (sulfite-forming)

Comments: Requires FeII. The enzyme from Escherichia coli also acts on pentanesulfonate, 3-(N-morpholino)propanesulfonate and 2-(1,3-dioxoisoindolin-2-yl)ethanesulfonate, but at lower rates.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 197809-75-9


1. Eichhorn, E., Van Der Poeg, J.R., Kertesz, M.A. and Leisinger, T. Characterization of α-ketoglutarate-dependent taurine dioxygenase from Escherichia coli. J.Biol. Chem. 272 (1997) 23031-23036. [PMID: 9287300]

[EC created 2000]

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