IUBMB Enzyme Nomenclature

EC 1.14.11.24

Accepted name: 2'-deoxymugineic-acid 2'-dioxygenase

Reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = mugineic acid + succinate + CO2

For diagram click here.

Other name(s): IDS3

Systematic name: 2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)

Comments: Requires iron(II). It is also likely that this enzyme can catalyse the hydroxylation of 3-epihydroxy-2'-deoxymugineic acid to form 3-epihydroxymugineic acid.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 133758-62-0

References:

1. Nakanishi, H., Yamaguchi, H., Sasakuma, T., Nishizawa, N.K. and Mori, S. Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores. Plant Mol. Biol. 44 (2000) 199-207. [PMID: 11117263]

2. Kobayashi, T., Nakanishi, H., Takahashi, M., Kawasaki, S., Nishizawa, N.K. and Mori, S. In vivo evidence that Ids3 from Hordeum vulgare encodes a dioxygenase that converts 2'-deoxymugineic acid to mugineic acid in transgenic rice. Planta 212 (2001) 864-871. [PMID: 11346963]

[EC 1.14.11.24 created 2005]


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