IUBMB Enzyme Nomenclature


Accepted name: 2-aminoethylphosphonate dioxygenase

Reaction: (2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (2-amino-1-hydroxyethyl)phosphonate + succinate + CO2

Other name(s): phnY (gene name)

Systematic name: (2-aminoethyl)phosphonate,2-oxoglutarate:oxygen oxidoreductase (1-hydroxylating)

Comments: Requires Fe2+ and ascorbate. The enzyme, characterized from an uncultured marine bacterium, is involved in a (2-aminoethyl)phosphonate degradation pathway.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. McSorley, F.R., Wyatt, P.B., Martinez, A., DeLong, E.F., Hove-Jensen, B. and Zechel, D.L. PhnY and PhnZ comprise a new oxidative pathway for enzymatic cleavage of a carbon-phosphorus bond. J. Am. Chem. Soc. 134 (2012) 8364-8367. [PMID: 22564006]

[EC created 2014]

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