IUBMB Enzyme Nomenclature


Accepted name: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

Reaction: anthranilate + NAD(P)H + 2 H+ + O2 = catechol + CO2 + NAD(P)+ + NH3

For diagram of reaction click here.

Other name(s): anthranilate hydroxylase; anthranilic hydroxylase; anthranilic acid hydroxylase

Systematic name: anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)

Comments: Requires Fe2+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 9059-17-0


1. Kobayashi, S. and Hayaishi, O. Anthranilic acid conversion to catechol (Pseudomonas). Methods Enzymol. 17A (1970) 505-510.

2. Taniguchi, H., Hatanaka, M., Kuno, S., Hayaishi, O., Nakajima, M. and Kurihara, N. Enzymatic formation of catechol from anthranilic acid. J. Biol. Chem. 239 (1964) 2204-2211.

[EC created 1972]

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