IUBMB Enzyme Nomenclature


Accepted name: terephthalate 1,2-dioxygenase

Reaction: terephthalate + NADH + H+ + O2 = (1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + NAD+

For diagram click here.

Other name(s): benzene-1,4-dicarboxylate 1,2-dioxygenase; 1,4-dicarboxybenzoate 1,2-dioxygenase

Systematic name: benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)

Comments: has been shown to contain a Rieske [2Fe-2S] cluster

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 162032-76-0


1. Schläfli, H.R., Weiss, M.A., Leisinger, T. and Cook, A.M. Terephthalate 1,2-dioxygenase system from Comamonas testosteroni T-2; purification and some properties of the oxygenase component. J. Bacteriol. 176 (1994) 6644-6652. [PMID: 7961417]

[EC created 1999]

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