IUBMB Enzyme Nomenclature


Accepted name: 4-chlorophenylacetate 3,4-dioxygenase

Reaction: 4-chlorophenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+

For diagram click here.

Systematic name: 4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)

Comments: A system, containing a reductase and an iron-sulfur oxygenase, and no independent ferredoxin. Requires Fe2+. Also acts on 4-bromophenyl acetate.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, CAS registry number: 105006-00-6


1. Markus, A., Krekel, D. and Lingens, F. Purification and some properties of component A of the 4-chlorophenylacetate 3,4-dioxygenase from Pseudomonas species strain CBS. J. Biol. Chem. 261 (1986) 12883-12888. [PMID: 3745216]

[EC created 1989 as EC, transferred 1992 to EC]

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