IUBMB Enzyme Nomenclature


Accepted name: pyrrole-2-carboxylate monooxygenase

Reaction: pyrrole-2-carboxylate + NADH + H+ + O2 = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O

Other name(s): pyrrole-2-carboxylate oxygenase

Systematic name: pyrrole-2-carboxylate,NADH:oxygen oxidoreductase (5-hydroxylating)

Comments: A flavoprotein (FAD). The enzyme initiates the degradation of pyrrole-2-carboxylate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Hormann, K. and Andreesen, J.R. Purification and characterization of a pyrrole-2-carboxylate oxygenase from Arthrobacter strain Py1. Biol. Chem. Hoppe-Seyler 375 (1994) 211-218. [PMID: 8011178]

2. Becker, D., Schrader, T. and Andreesen, J.R. Two-component flavin-dependent pyrrole-2-carboxylate monooxygenase from Rhodococcus sp. Eur. J. Biochem. 249 (1997) 739-747. [PMID: 9395321]

[EC created 2011]

Return to EC 1.14.13 home page
Return to EC 1.14 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page