IUBMB Enzyme Nomenclature


Accepted name: questin monooxygenase

Reaction: questin + NADPH + H+ + O2 = demethylsulochrin + NADP+

Glossary: questin = 3,8-dihydroxy-1-methoxy-6-methylanthracene-9,10-dione
demethylsulochrin = 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoic acid

Other name(s): questin oxygenase

Systematic name: questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)

Comments: The enzyme cleaves the anthraquinone ring of questin to form a benzophenone. Involved in the biosynthesis of the seco-anthraquinone (+)-geodin.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 115232-45-6


1. Fujii, I., Ebizuka, Y. and Sankawa, U. A novel anthraquinone ring cleavage enzyme from Aspergillus terreus. J. Biochem. (Tokyo) 103 (1988) 878-883. [PMID: 3182756]

[EC created 1992]

Return to EC 1.14.13 home page
Return to EC 1.14 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page