IUBMB Enzyme Nomenclature


Accepted name: imidazoleacetate 4-monooxygenase

Reaction: 4-imidazoleacetate + NADH + H+ + O2 = 5-hydroxy-4-imidazoleacetate + NAD+ + H2O

Other name(s): imidazoleacetic hydroxylase; imidazoleacetate hydroxylase; imidazoleacetic monooxygenase

Systematic name: 4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)

Comments: A flavoprotein (FAD). Formerly EC

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-65-6


1. Maki, Y., Yamamoto, S., Nozaki, M. and Hayaishi, O. Studies on monooxygenases. II. Crystallization and some properties of imidazole acetate monooxygenase. J. Biol. Chem. 244 (1969) 2942-2950. [PMID: 5772468]

[EC created 1965 as EC, transferred 1972 to EC]

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