Reaction: 4-imidazoleacetate + NADH + H+ + O2 = 5-hydroxy-4-imidazoleacetate + NAD+ + H2O
Other name(s): imidazoleacetic hydroxylase; imidazoleacetate hydroxylase; imidazoleacetic monooxygenase
Systematic name: 4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)
Comments: A flavoprotein (FAD). Formerly EC 188.8.131.52.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-65-6
1. Maki, Y., Yamamoto, S., Nozaki, M. and Hayaishi, O. Studies on monooxygenases. II. Crystallization and some properties of imidazole acetate monooxygenase. J. Biol. Chem. 244 (1969) 2942-2950. [PMID: 5772468]