Reaction: 6-oxocineole + NADPH + H+ + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + NADP+ + H2O
For diagram of reaction click here.
Other name(s): 6-oxocineole oxygenase
Systematic name: 6-oxocineole,NADPH:oxygen oxidoreductase
Comments: The product undergoes non-enzymic cleavage and subsequent ring closure to form the lactone 4,5-dihydro-5,5-dimethyl-4-(3-oxobutyl)furan-2(3H)-one.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 122933-80-6
References:
1. Williams, D.R., Trudgill, P.W. and Taylor, D.G. Metabolism of 1,8-cineole by a Rhodococcus species - ring cleavage reactions. J. Gen. Microbiol. 135 (1989) 1957-1967.