IUBMB Enzyme Nomenclature


Accepted name: benzoyl-CoA 3-monooxygenase

Reaction: benzoyl-CoA + NADPH + H+ + O2 = 3-hydroxybenzoyl-CoA + NADP+ + H2O

Other name(s): benzoyl-CoA 3-hydroxylase

Systematic name: benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)

Comments: the enzyme from the denitrifying bacterium Pseudomonas KB740 catalyses a flavin-requiring reaction (FAD or FMN). Benzoate is not a substrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 151616-61-4


1. Niemetz, R., Altenschmidt, U., Herrmann, H. and Fuchs, G. Benzoyl-coenzyme-A 3-monooxygenase, a flavin-dependent hydroxylase. Purification, some properties and its role in aerobic benzoate oxidation via gentisate in a denitrifying bacterium. Eur. J. Biochem. 227 (1995) 161-168. [PMID: 7851381]

[EC created 1999]

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