IUBMB Enzyme Nomenclature


Accepted name: 2-hydroxyquinoline 8-monooxygenase

Reaction: quinolin-2-ol + NADH + H+ + O2 = quinolin-2,8-diol + NAD+ + H2O

Other name(s): 2-oxo-1,2-dihydroquinoline 8-monooxygenase

Systematic name: quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating)

Comments: requires iron. Quinolin-2-ol exists largely as the quinolin-2(1H)-one tautomer.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 166799-89-9


1. Rosche, B., Tshisuaka, B., Fetzner, S. and Lingens, F. 2-Oxo-1,2-dihydroquinoline 8-monooxygenase, a two-component enzyme system from Pseudomonas putida 86. J. Biol. Chem. 270 (1995) 17836-17842. [PMID: 7629085]

[EC created 1999]

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